منابع مشابه
Bilateral diaphragm weakness.
Paralysis of the diaphragm occurring as a result of damage to the phrenic nerves during thoracic and neck surgery is well recognised.' 2 It is likely that weakness, as opposed to complete paralysis, of the diaphragm could occur after less severe trauma to the phrenic nerves. We describe a patient who developed bilateral diaphragm weakness after complicated surgery on a cervical disc, with subse...
متن کاملDiaphragm weakness in Charcot-Marie-Tooth disease.
Two patients are described with Charcot-Marie-Tooth disease and chronic peripheral neuropathy. Both had dyspnoea, orthopnoea, and evidence of severe diaphragm weakness. Expiratory muscle function was well preserved and abnormalities of gas exchange during sleep were only minor.
متن کاملDiaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction.
We previously demonstrated that diaphragm muscle weakness is present in experimental pulmonary arterial hypertension (PH). However, the nature of this diaphragm weakness is still unknown. Therefore, the aim of this study was to investigate whether changes at the sarcomeric level contribute to diaphragm weakness in PH. For this purpose, in control rats and rats with monocrotaline-induced PH, con...
متن کاملCaspase activation contributes to endotoxin-induced diaphragm weakness.
Infections produce significant respiratory muscle weakness, but the mechanisms by which inflammation reduces muscle force remain incompletely understood. Recent work suggests that caspase 3 releases actin and myosin from the contractile protein lattice, so we postulated that infections may reduce skeletal muscle force by activating caspase 3. The present experiments were designed to test this h...
متن کاملHyperglycemia-induced diaphragm weakness is mediated by oxidative stress
INTRODUCTION A major consequence of ICU-acquired weakness (ICUAW) is diaphragm weakness, which prolongs the duration of mechanical ventilation. Hyperglycemia (HG) is a risk factor for ICUAW. However, the mechanisms underlying HG-induced respiratory muscle weakness are not known. Excessive reactive oxygen species (ROS) injure multiple tissues during HG, but only one study suggests that excessive...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1987
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688708000520